B12 Tx

Vitamin B12 Shots Are Very Effective
An untreated vitamin B12 deficiency can lead to neurological problems or pernicious anemia, which occurs when your body doesn't have enough B12 to produce the amount of red blood cells it needs (16). Vitamin B12 shots are the most common way to prevent or treat a deficiency. The injections are prescribed by a doctor and given intramuscularly, or into muscle. Injections are usually given as hydroxocobalamin or cyanocobalamin. These are very effective at raising blood levels of B12 and preventing/reversing a deficiency.
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  • Dr. Robert Ambrozic MD
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  • B12 Tx
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  • Age-Related Macular Degeneration
  • Age-related macular degeneration is a condition that causes you to gradually lose central vision, usually in both eyes. In people aged 50 and over, adequate consumption of vitamin B12 is thought to be important for maintaining good vision and protecting against macular degeneration. In one large study, 5,200 women received 1,000 mcg of vitamin B12 daily, as well as other B vitamins and folic acid. 7 years later, the study found a 35% lower risk of age-related macular degeneration among the women who took the supplements. Although the reduction in risk can't be attributed to vitamin B12 only, it does suggest that getting enough may be important.
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  • Our personal recommendations for vitamin B12 when used for medicinal purposes are methylcobalamin and adenosylcobalamin, which are both readily bioavailable. Both cyanocobalamin and hydroxocobalamin must first be converted into methylcobalamin and adenosylcobalamin before they can be used in the body. These forms are referred to as B12 coenzymes or bio-identical vitamin B12 forms.
What is B12?
Vitamin B-12 belongs to the family of cobalamins. It is available in all animal-derived foods, and is absorbed at a rate of 5 mcg per day. After being ingested, vitamin B-12 becomes bound to intrinsic factor, a protein secreted by gastric parietal cells. The vitamin B-12/intrinsic factor complex is absorbed in the terminal ileum by cells with specific receptors for the complex. The absorbed complex is then transported via plasma and stored in the liver.
Intestinal Malabsorption?

Since the liver stores 2,000 to 5,000 mcg vitamin B-12 (adequate for up to 5 years), dietary deficiency of cobalamin (Cbl) is rare. In most cases, vitamin B-12 deficiency is due to an inability of the intestine to absorb the vitamin, which may result from an autoimmune disease that reduces the production or blocks the action of intrinsic factor, or from other diseases that result in intestinal malabsorption. The most frequent underlying cause of vitamin B-12 deficiency is pernicious anemia, which is associated with decreased production of intrinsic factor.

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